NAD+, NMN, and Telomuse Are Now Available in Mumbai — Here Is What They Actually Do for Your Skin and Who They Are For

Key Takeaways

• The NAD+·NMN·Telomuse Complex is one of four treatments Dr Akansha sourced directly from CosmoBeauty Seoul 2026 (May 27–29, COEX) — now available at Glam Korean Skin Studio in Andheri West as part of the clinic’s cellular anti-ageing programme.
• The complex addresses skin ageing at the cellular energy and DNA integrity level — where NAD+ depletion, reduced sirtuin activity, and telomere shortening combine to reduce the skin’s renewal, repair, and collagen synthesis capacity in the forties and beyond.
• NAD+ is the coenzyme that powers cellular energy production and DNA repair. NMN is its most bioavailable precursor. Telomuse supports telomere integrity — addressing the cellular senescence driver of visible skin ageing that no surface treatment reaches.
• Delivered intravenously for maximum bioavailability. Initial course of 4 to 6 weekly sessions, monthly maintenance thereafter. Most appropriate for clients in their late thirties and beyond whose skin ageing is progressing beyond what surface treatments are addressing.
• Combines with Profhilo (for dermal structural quality), Vampire Facial PRP (for cellular vitality), and IV Glow Drips (for antioxidant support) as the most comprehensive cellular-level anti-ageing programme available at Glam.

In May 2026, I attended CosmoBeauty Seoul — the annual international aesthetic medicine conference at COEX, Seoul — and returned with four treatments that represented the most significant advances in Korean aesthetic medicine I had encountered since establishing Glam Korean Skin Studio. The blog series has covered the CosmoBeauty treatments before: PDRN+VB Complex (blog-08 supporting link), Korean Pigmentation Correction Therapy (blog-15 supporting link), Korean Skin Rejuvenation Treatment (blog-13).

The NAD+·NMN·Telomuse Complex has been the most frequently asked about of the four — and the one that has generated the most substantive questions from clients who have read about cellular anti-ageing science in global wellness media and want to understand whether the clinical version available at Glam is the real thing.

It is. This blog is the complete explanation: what NAD+, NMN, and Telomuse each do at the cellular level, what their specific effects on skin ageing are, why IV delivery rather than oral supplementation is the clinical standard, who is the appropriate candidate, and how this treatment fits into the broader programme at Glam for clients who want to address their skin at every level simultaneously.

The Problem This Treatment Addresses — Cellular Energy Decline

Every treatment in Glam’s menu addresses skin ageing at a specific level: surface peels address the uppermost layers; Profhilo addresses dermal collagen and elastin; HIFU addresses structural SMAS; Vampire Facial PRP addresses cellular vitality and vascularity. None of these treatments addresses the mitochondrial energy capacity of skin cells — the fundamental cellular metabolism that drives all of these processes.

Mitochondria are the energy-producing organelles in every skin cell. Their output — in the form of ATP (adenosine triphosphate), the universal cellular energy currency — powers: collagen synthesis by fibroblasts, DNA damage repair after UV exposure, the cellular turnover that keeps the skin renewing at an appropriate rate, and the inflammation-dampening mechanisms that prevent the chronic low-grade inflammatory state that accelerates visible skin ageing.

Mitochondrial function declines with age — and the most critical molecule in this decline is NAD+. NAD+ is the coenzyme that mitochondria require to run their energy production reactions. Without adequate NAD+, mitochondria cannot produce ATP efficiently, and the cellular processes that ATP powers — including all of the above — slow down. NAD+ levels decline approximately 50% between the ages of 40 and 60. The skin’s visible deterioration in this decade is, in significant part, a manifestation of this NAD+ depletion.

The Three Components — What Each Does

NAD+ — The Cellular Engine Fuel

Nicotinamide adenine dinucleotide is the central coenzyme in cellular energy metabolism. Beyond energy production, NAD+ is required for the activity of sirtuins — the family of proteins sometimes called longevity proteins — which regulate cellular stress response, DNA repair, inflammation, and epigenetic gene expression patterns. Reduced NAD+ means reduced sirtuin activity, which means reduced cellular resilience to the stressors (UV, pollution, metabolic demands) that drive visible skin ageing. IV NAD+ at therapeutic doses restores intracellular NAD+ to levels that oral supplementation cannot consistently achieve — the first-pass liver metabolism of orally consumed NAD+ limits the amount that reaches skin cells at meaningful concentrations.

NMN — The Bioavailable Precursor

Nicotinamide mononucleotide is the immediate biochemical precursor to NAD+ — the body’s most efficient route to intracellular NAD+ elevation. NMN enters cells and is converted to NAD+ within the cell, bypassing some of the bioavailability limitations of NAD+ itself. In the complex, NMN works alongside directly administered NAD+ to ensure sustained intracellular elevation — the NAD+ addresses the immediate deficit while NMN supports the ongoing synthesis pathway. Research in longevity science (notably from David Sinclair’s lab at Harvard and Japanese clinical studies) has documented NMN’s consistent effect on NAD+ elevation and its downstream benefits for cellular metabolism and DNA repair.

Telomuse — The Telomere Support Component

Telomeres — the protective chromosomal caps that shorten with each cell division — are the molecular clock of cellular ageing. Skin cells divide frequently (the epidermis renews approximately every 28 to 40 days, accelerated by UV damage), and cumulative telomere shortening across years of this division produces a progressively senescent skin cell population. Senescent cells do not divide or renew the skin; they produce inflammatory cytokines (the senescence-associated secretory phenotype, SASP) that damage surrounding cells. This is one of the primary mechanisms of the visible skin ageing that accumulates in the forties — a progressive replacement of functional skin cells by senescent inflammatory cells. Telomuse, the proprietary component of this complex, is formulated to support telomere integrity and reduce the rate of pathological shortening — addressing this cellular senescence driver at its source.

What This Means for Your Skin — The Clinical Effects

The cellular-level mechanisms above translate to the following skin quality improvements over the course of treatment:

• Improved cellular renewal rate — NAD+-replete skin cells cycle through their renewal process more efficiently, producing the surface turnover improvement that peels produce from outside but that the complex produces from inside
• Better UV and oxidative damage repair — NAD+-dependent DNA repair enzymes (PARP-1 and others) operate at higher capacity, reducing the accumulation of UV-induced DNA damage that manifests as pigmentation, texture change, and increased skin cancer risk
• Improved collagen synthesis — fibroblasts with adequate NAD+ produce collagen more efficiently; the energy substrate that collagen synthesis demands is more readily available
• Reduced inflammaging — sirtuin activity reduces the chronic low-grade inflammatory signalling that senescent skin cells produce; the inflammatory load on surrounding healthy cells decreases
• Overall skin vitality improvement — the cumulative effect of improved cellular energy, repair, and renewal is a skin quality that clients most often describe as “my skin looks more like itself again” — not a dramatic visible transformation but a restoration of the vitality and renewal quality that NAD+ depletion had progressively reduced

How the NAD+·NMN·Telomuse Complex Fits Into Glam’s Anti-Ageing Programme

The cellular complex addresses the level of skin ageing that no other treatment in Glam’s menu reaches — mitochondrial energy and DNA integrity. This makes it complementary to, rather than competing with, every other treatment:

• + Profhilo — cellular energy support from NAD+·NMN·Telomuse amplifies the fibroblast response to Profhilo’s collagen and elastin stimulation; cells with adequate energy produce more collagen from the same stimulus
• + Vampire Facial PRP — PRP’s growth factor stimulation of fibroblast proliferation and collagen synthesis is more effective in cells with adequate NAD+ to power the synthesis pathways
• + IV Glow Drips — the glutathione antioxidant layer of IV Glow Drips complements NAD+’s DNA repair function; antioxidants reduce the oxidative DNA damage that NAD+-dependent repair must address, reducing the demand on NAD+ reserves

For clients in their forties and beyond who want the most comprehensive anti-ageing programme available at Glam, the combination of NAD+·NMN·Telomuse (cellular energy and longevity), Profhilo (dermal structural quality), Vampire Facial PRP (cellular vitality and vascularity), and IV Glow Drips (antioxidant and brightening) addresses all four dimensions of skin ageing simultaneously — from the deepest cellular level to the surface.

What Clients Ask About NAD+·NMN·Telomuse

Can I just take NMN supplements orally instead?

Oral NMN supplementation produces some NAD+ elevation and has clinical evidence supporting its benefits in longevity research contexts. However, oral bioavailability is significantly lower than IV delivery due to first-pass liver metabolism — a meaningful proportion of orally consumed NMN is metabolised before reaching systemic circulation, and the fraction that reaches skin cells is further reduced by the distribution of oral supplements across all tissues. IV delivery achieves tissue concentrations that are not practically achievable through oral supplementation. For clients who want the full cellular benefit rather than a partial contribution, IV delivery at therapeutic doses is the appropriate clinical route.

Is this treatment safe and are there any side effects?

NAD+ and NMN have well-established safety profiles from both longevity research and clinical application. The most common experience during IV NAD+ infusion is a mild flushing or warmth sensation — this is managed by controlling the infusion rate (slower delivery reduces this sensation). Telomuse components are reviewed for individual suitability at the consultation. The treatment is not appropriate for clients with certain medical conditions (active cancer, specific cardiovascular conditions) — full medical history is reviewed at the consultation before the programme begins. Dr Akansha supervises all sessions at Glam; the treatment is not delegated to non-clinical staff.

How long before I notice results?

Cellular-level anti-ageing produces gradual, cumulative improvement rather than the immediate visible result of a surface peel or Hydrafacial. Most clients notice improved skin vitality, luminosity, and renewal quality at 4 to 6 weeks into the initial course — the cellular improvement becomes visible at the surface as the renewed cellular capacity expresses through the skin’s natural renewal cycle. The most significant and clinically meaningful results are typically apparent at 3 to 4 months of the initial course and maintenance programme.

The Most Advanced Anti-Ageing Science From CosmoBeauty Seoul 2026 — Now at Glam Korean Skin Studio, Andheri West

The NAD+·NMN·Telomuse Complex brings cellular longevity science into Glam’s clinical programme for clients whose skin ageing requires treatment at the level no surface or structural intervention reaches. The consultation determines whether this treatment is appropriate for your specific presentation and how it fits into your broader programme at Glam.

Book a Cellular Anti-Ageing Consultation at Glam Korean Skin Studio, Andheri West →
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